Preheat your oven to 350°F (175°C). Grease a 9x5-inch loaf pan or line it with parchment paper.
In a medium bowl, whisk together the flour, baking powder, baking soda, and salt. Set aside.
In a large mixing bowl, cream together the softened butter and granulated sugar until light and fluffy (about 3-4 minutes).
Add the eggs one at a time, mixing well after each addition.
Stir in the lemon zest, fresh lemon juice, and vanilla extract until well combined.
Gradually add the dry ingredient mixture to the wet ingredients, mixing until just combined. Be careful not to overmix!
Gently fold in the blueberries, ensuring they are evenly distributed throughout the batter.
Pour the batter into the prepared loaf pan and smooth the top with a spatula.
Bake in the preheated oven for 55-60 minutes, or until a toothpick inserted into the center comes out clean.
Once done, remove the bread from the oven and let it cool in the pan for about 10 minutes before transferring it to a wire rack to cool completely.
If desired, dust the cooled bread with powdered sugar for a lovely touch before slicing and serving.
Notes
Slice the bread into thick pieces and serve it on a rustic wooden board. Consider garnishing with fresh blueberries and a sprig of mint for a pop of color. Enjoy with a cup of tea or coffee!