Cook the penne pasta according to package instructions until al dente. Drain and set aside.
In a large pot, bring water to a boil and blanch the broccoli florets for 2 minutes. Drain and set aside.
In a large mixing bowl, combine the cooked pasta, shredded chicken, blanched broccoli, Alfredo sauce, garlic powder, onion powder, half of the cheddar cheese, and half of the mozzarella cheese. Stir well until everything is evenly coated.
Season with salt and pepper to taste, adjusting as necessary.
Transfer the mixture into a greased 9x13 inch baking dish.
In a small bowl, combine the breadcrumbs with olive oil and the remaining cheddar and mozzarella cheese. Mix until the breadcrumbs are coated.
Sprinkle the breadcrumb mixture evenly over the pasta mixture in the baking dish.
Bake in the preheated oven for 25-30 minutes, or until the top is golden and bubbly.
Remove from the oven and let it cool slightly. Garnish with fresh chopped parsley before serving.
Notes
Feel free to add more vegetables or use different types of cheese.